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KMID : 1225720200120010086
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Allergy, Asthma & Immunology Research : AAIR
2020 Volume.12 No. 1 p.86 ~ p.98
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Associated Factors for Asthma Severity in Korean Children: A Korean Childhood Asthma Study
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Lee Eun
Song Dae-Jin
Kim Woo-Kyung
Suh Dong-In
Baek Hey-Sung
Shin Mee-Yong
Yoo Young
Kim Jin-Tack
Kwon Ji-Won
Jang Gwang-Cheon
Lim Dae-Hyun
Yang Hyeon-Jong
Kim Hwan-Soo
Seo Ju-Hee
Woo Sung-Il
Woo Sung-Il
Kim Hyung-Young
Shin Youn-Ho
Lee Ju-Suk
Yoon Ji-Sun
Jung Sung-Su
Han Min-Kyu
Eom Eun-Jin
Yu Jin-Ho
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Abstract
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Purpose: Childhood asthma has a considerable social impact and economic burden, especially in severe asthma. This study aimed to identify the proportion of childhood asthma severity and to evaluate associated factors for greater asthma severity.
Methods: This study was performed on 667 children aged 5?15 years with asthma from the nationwide 19 hospitals in the Korean childhood Asthma Study (KAS). Asthma was classified as mild intermittent, mild persistent, and moderate/severe persistent groups according to the National Asthma Education and Prevention Program recommendations. Multinomial logistic regression models were used to identify the associated factors for greater asthma severity.
Results: Mild persistent asthma was most prevalent (39.0%), followed by mild intermittent (37.6%), moderate persistent (22.8%), and severe persistent asthma (0.6%). Onset later than 6 years of age (adjusted odds ratio [aOR], 1.69 for mild persistent asthma; aOR, 1.92 for moderate/severe persistent asthma) tended to increase asthma severity. Exposure to environmental tobacco smoke (aOR, 1.53 for mild persistent asthma; aOR, 1.85 for moderate/severe persistent asthma), and current dog ownership with sensitization to dog dander (aOR, 5.86 for mild persistent asthma; aOR, 6.90 for moderate/severe persistent asthma) showed increasing trends with greater asthma severity. Lower maternal education levels (aOR, 2.32) and no usage of an air purifier in exposure to high levels of outdoor air pollution (aOR, 1.76) were associated with moderate/severe persistent asthma.
Conclusions: Modification of identified environmental factors associated with greater asthma severity might help better control childhood asthma, thereby reducing the disease burden due to childhood asthma.
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KEYWORD
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Child, asthma, severity, risk factor, environmental exposure, smoke, dogs, education status, air pollution
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